To get our refreshing, clean scents, Puracy products use natural essential oils like mint, cucumber, and orange. 2022 Campaign for Safe Cosmetics, a program of, Methylisothiazolinone and Methylchloroisothiazolinone, Menstrual Care Products and Toxic Chemicals, Ethanolamine Compounds (MEA, DEA, TEA And Others), http://www.ewg.org/skindeep/ingredient/703924/METHYLCHLOROISOTHIAZOLINONE/, http://www.cosmeticsinfo.org/ingredient/methylisothiazolinone-and-methylchloroisothiazolinone, https://www.ewg.org/skindeep/ingredients/703924-methylchloroisothiazolinone/, https://www.cir-safety.org/sites/default/files/MI_MCI.pdf. 27 products found from 17 suppliers for "Methylchloroisothiazolinone" DOI: Yu SH, et al. 5% and exposure is associated with occupation, cosmetic products, and household products. * A preservative Kamaleo Color Shampoo Mais Cor Kamaleo Color Condicionador Mais Cor Kamaleo Color Creme De Pentear Mais Cor Zero Silver Shampoo Dove Go Fresh Face Cleanser RENPURE Argan Oil Luxurious Shampoo Telepoint family Rose Scented Hand Soap UrbanBotanics Aloe Vera Gel ARAVIA Professional Lactica Exfoliate . The list includes cleaning products, detergents, lotions, sunscreens, shampoos, conditioners, hair coloring, body washes, mascara, shaving cream, make-up remover, liquid soaps, and baby products including wipes, lotions and shampoos. It's most often seen in shampoos and other rinse-off products. CAS# 26172-55-4. There is a good chance that even if you are sensitive to MI, you may not be sensitive to the MI/MCI combination. the methylchloroisothiazolinone and methylisothiazolinone are components in biocides, for use as preservatives in oil and cooling fluids, soaps, latex emulsions, slime control in paper mills, jet fuels, milk sampling, radiography, printing inks, moist toilet paper, detergents, shampoos, hair conditioners, hair & body gels, bubble baths, skin Cleaning that puts people + our planet first. Methylchloroisothiazolinone is known by the registered tradename Kathon CG when used in combination with . methylchloroisothiazolinone productsthe courtyard wickersley menu. It is approved by the CIR for use in cosmetics. It is often at a very low concentration indeed in fact. Agents classified by the IARC monographs, volumes 1123. Menu . Journal of the American College of Toxicology, 11(1). It is . Love it or return it within 30 days for a full product refund. MI was initially used occupationally, in paints, adhesives/glues and cleaners etc, as a mixture with methylchloroisothiazolinone (MCI). Methylisothiazolinone is a synthetic chemical used in consumer products for its antimicrobial properties. LOW Cancer MODERATE Allergies & Immunotoxicity LOW Developmental and Reproductive Toxicity HIGH Use Restrictions Ingredient concerns CONCERNS DATA SOURCES Its function is to inhibit the growth of bacteria [1] [2]. [8] NIOSH Methylisothiazolinone Guidelines Accessed Online: https://www.cir-safety.org/sites/default/files/MI_MCI.pdf. Code must be entered into Promo Code box at checkout. International journal of toxicology, 29(4 suppl), 187S-213S. MIT meets the EPA's safer choice ingredient list. Search Keywords. (2015). Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Subungual Hematoma: Drainage for Immediate Relief, Blueberry Muffin Rash on Babies: How to Recognize and Treat. TOP PRODUCTS Guides and resources for easy product selection INGREDIENTS Learn how to read your hair product labels DIY PRODUCTS Easy-to-make recipes for all your haircare needs BEST OF THE BEST Community member favorites . Methylisothiazolinone (MI) is a common preservative used in the personal care industry, however there are now concerns it may trigger allergies in some people. * Please read TIA's articles on Why Products Need Preservatives and Preservatives and Are They Safe, Products with Methylchloroisothiazolinone. Methylchloroisothiazolinone (CMIT): 5-Chloro-2-methyl-4-isothiazolin-3-one and MCI. Methylisothiazolinone (MI) is a preservative. The Best 20 Invisible Sunscreens for Dark Skin, The 8 Best Loofah Alternatives and How to Choose One, 5-chloro-2-methyl-4-isothiazolin-3-one hydrochloride. It can reduce the inflammation, swelling, and bleeding of, Learn about how the vitamin C and other nutrients in beets can help with your skin, including with anti-aging, antioxidant properties, and acne, Panthenol appears in food, supplements, and hygienic products of a wide variety. [3][4] Both chemicals inhibit bacterial growth in cosmetic products on their own, but they are most commonly used as a mixture in products. * A preservative * Please read TIA's articles on Why Products Need Preservatives and Preservatives and Are They Safe Functions: Methylchloroisothiazolinone is a preservative often used in cosmetics and beauty products for its antibacterial and anti-fungal effects, according to Wikipedia. MCI is often combined with methylisothiazolinone (MI) under the brand name Kathon CG. The bad news with it though is that it can sensitize the skin easily (its a so-called non-fragrance allergen). Methylchloroisothiazolinone was first used in cosmetics in the 1970s. Preservatives help keep people safe by preventing the growth of bacteria and mold in products while they're used at home. Its not permitted to be used alone, but only with its BFF, methylisothiazolinone (MI), another icky preservative. [9] Lundov, M. D., Krongaard, T., Menn, T. L., & Johansen, J. D. (2011). In 2016, the Canadian goverrnment revised its Hot List to include additional warnings about this ingredient. *Youre subscribing to BCPPs Campaign for Safe Cosmetics email list. The authors proposed that the prevalence of . Dermatologists should be aware of this situation, and counsel patients to avoid products containing MCI and/or MI. This will help when you need to learn ingredients to read . FORMULATIONS with METHYLCHLOROISOTHIAZOLINONE. Since 2005, it has been widely used in cosmetics and household products, such as moist wipes, shampoos, cleaners and liquid laundry products. Methylisothiazolinone contact allergy: a review. Methylchloroisothiazolinone is a preservative often used in cosmetics and beauty products for its antibacterial and anti-fungal effects, according to Wikipedia. Those reactions were mostly related to leave-in products in the 1980s and 1990s. methylchloroisothiazolinone/methylisothiazolinone (mci/mi) is a preservative mixture at a fixed combination (ratio 3/1), which is commonly used in cosmetic and industrial applications and can be found in cosmetics, especially shampoos, dermatological products, mainly sunscreens, household cleaning products, paints, moist toilet paper, Many synthetic fragrances are derived from petroleum products. Kathon, Kathon CG, Kathon 886. A study found that many products marketed to babies and children contained this potentially irritating ingredient, even if their packaging stated that the product was designed for sensitive skin, or was described as "gentle" or "hypoallergenic.". Methylchloroisothiazolinone is found in many water-based personal care products and cosmetics. Our website services, content, and products are for informational purposes only. How is this different than cleaning with vinegar. We have removed MI from the vast majority of our leave-on personal care products. Available online: https://www.ewg.org/skindeep/ingredient/703924/METHYLCHLOROISOTHIAZOLINONE/December 20, 2016. Methylisothiazolinone Where is Methylisothiazolinone found? (2016). This Energizing Essence is an ultra-sensorial light fluid emulsion inspired by Asian skincare for an invigorating wake-up. . Final report of the safety assessment of methylisothiazolinone. HAZARDS IDENTIFICATION . [4] Methylisothiazolinone and Methylchloroisothiazolinone Available Online: http://www.cosmeticsinfo.org/ingredient/methylisothiazolinone-and-methylchloroisothiazolinone. Available online: http://www.healthychild.org/the-5-worst-ingredients-in-kids-body-care-products/ December 20, 2016. (2010). A lot of cleaning products do not even list their ingredients . Methylisothiazolinone (also known as MIT) is a common preservative found in home and skincare products. Common concerns See how this product scores for common concerns. The Advantages and Disadvantages of Chlorhexidine Mouthwash. It is also known as 3(2H) . This totally unpronounceable ingredient (lets take a shortcut: MCI) is a super effective preservative with both antibacterial and antifungal effects that works at very low concentrations. DOWNLOAD THE APP. Methylchloroisothiazolinone has been linked with allergic reactions and chemical burns (4). Contact dermatitis to methylisothiazolinone. Methylisothiazolinone. We've got eight alternatives to try. Offer expires 11:59 p.m. PST 11/10/22. Acute Inhalation toxicity study in rate (methylisothiazolinone 53.52% active ingredient). Safety Measures/Side Effects: In high concentrations Methylchloroisothiazolinone can cause chemical burns and it is a skin and membrane irritant. If you are allergic, read labels and avoid products with Methylisothiazolinone (MIT) or Methylchloroisothiazolinone (CMIT). International journal of toxicology, 29(4 suppl), 187S-213S. Does Beetroot Offer Benefits for Your Skin? In cleaning products, where manufacturers arent required to list all their ingredients on product labels, choose toxic chemical free alternatives without preservatives. Final report of the safety assessment of methylisothiazolinone. Methylchloroisothiazolinone. [6] This may be a concern to factory workers who are exposed to high concentrations of MIT. Patch testing for methylisothiazolinone and methylchloroisothiazolinone-methylisothiazolinone contact allergy. Black-Owned Brands. [9] In a clinical study, researchers found that dermal irritation most commonly occurs in products with CMIT and MIT/CMIT mixtures, but is not as common in products with only MIT. Methylisothiazolinone contact allergy: a review. Earn Rewards, get samples, Sign up and SAVE today, Ouidad Water Works Shampoo (and a sample package for a reader to review). Pure Methylchloroisothiazolinone is not commercially available. International journal of toxicology, 29(4 suppl), 187S-213S. What is methylchloroisothiazolinone? Description: METHYLCHLOROISOTHIAZOLINONE: Methylchloroisothiazolinone (also known as MCI) is a common ingredient often used in cosmetics and beauty products as a preservative. Methylchloroisothiazolinone and Methylisothiazolinone are two ingredients used in skincare and cosmetics formulations to help preserve products against the growth of bacteria, yeasts, and fungi. Together, we can make beauty safer for all. These preservatives are known to be corrosive to skin, irritating to eyes, and toxic to fish. Brussels, 12 December 2013. [14] Burnett, C. L., Bergfeld, W. F., Belsito, D. V., Klaassen, C. D., Marks, J. G., Shank, R. C., & Andersen, F. A. Available online: https://householdproducts.nlm.nih.gov/cgi-bin/household/brands?tbl=chem&id=71&query=methylchloroisothiazolinone&searchas=TblChemicalsJanuary 23, 2107. [1] [2]. Currently, there are no National Institute for Occupational Safety and Health (NIOSH) guidelines to limit MIT/CMIT exposure in the workplace. One of the most commmented on blog posts I have done recently was the one on the preservative combination of methylchloroisothiazolinone and methylisothiazolinone. Methylisothiazolinone and methylchloroisothiazolinone. The rate of contact allergy is about 8 percent. Blau syndrome is a rare disease that causes arthritis symptoms, like pain and form changes in the joints, skin rashes and discoloration, and eye, While sunscreen is important no matter the color of your skin, certain formulas are known to leave a white cast on dark skin. Together they have a broad spectrum antimicrobial effect but are permitted to be usedonly in rinse-off products (under 0.0015%). It is also used in many industrial processes, such as paint and paper manufacturing, metalworking, mining, and sanitizing. Kathon was used in various rinse-off and leave-on formulations including hair products, shampoos, skin care products, bath products, eye and facial makeup, wet wipes and . The list includes cleaning products, detergents, lotions, sunscreens, shampoos, conditioners, hair coloring, body washes, mascara, shaving cream, make-up remover, liquid soaps, and baby products including wipes, lotions and shampoos [1]. It was largely removed from most cosmetic products except for those with only short duration skin contact such as rinse-offs, although its inclusion in certain forms makes it more acceptable to sensitive users. The TIA community consists of our trusted reviewers. It is part of a group of chemicals known as isothiazolinones, the most potent allergens on the consumer market. It is most often applied to cleaning products as a synthetic preservative. DEVELOPMENT AND VALIDATION OF AN ANALYTICAL METHOD FOR THE DETERMINATION OF METHYLISOTHIAZOLINONE AND METHYLCHLOROISOTHIAZOLINONE IN COSMETIC PRODUCTS USING MATRIX SOLID-PHASE DISPERSION. ARAVIA Professional Lactica Exfoliate 10%, Alberto Vo5 Herbal Escape Balancing Conditioner, Hidraderm ciclos Serum Vitamina C Hidraderm Ciclos, St. Botanica Argan Oil Ultra Nourishing Body Wash, Equate Kids 3-In-1 Shampoo, Conditioner, & Body Wash, Unscented, Hollywood By Dr. Rey Anti-Aging Facial Creme, Studio Selection Micellar Cleansing Water, Veganis Leche Extra Humectante Para Manos Y Cuerpo, skinology Niacinamide + 3D Hyaluron Serum. . Accessed April 26, 2022. methylchloroisothiazolinone products These preservatives, like many others, regularly draw the attention of the cosmetics media. For best results, you should see a doctor as soon as possible to have your subungual hematoma drained. I believe by learning Trichology (the study of hair and scalp) you can better understand your hair's needs and behaviors. Substances like MI and MCI are used in many haircare products, because they protect them from spoiling. (2010). (2010). Products Name: Product Characteristics: Suggested Application: Biocides: MOSV DA: 50% di-n-decyldimethylammoniumchloride (DDAC) It is a liquid Disinfectants. The preservative can still be used in rinse-off products such as shampoos and shower gels at a maximum concentration of 0.0015 percent of a mixture in the ratio 3:1 of MCI/MI.. It is part of a group of chemicals known as isothiazolinones, the most potent allergens on the consumer market. Also remember that because there are no federal criteria dictating standards for what makes a cleaning product natural, a multitude of so-called natural cleaners contain this toxic chemical. British Journal of Dermatology, 165(6), 1178-1182. Products: shampoo, baby shampoo, hair conditioner, hair spray and hair color Methylchloroisothiazolinone is found in a multitude of products, including those claiming to be natural. Many people are. Thanks. Autopsies revealed that death was due to reddened lungs and swollen intestines. What Is Butylene Glycol and Is It Bad for My Health? shampoos), and suggested that due conflicting evidence MCI and MI should be banned in 'leave-on' products (e.g. Although it can be used alone, methylchloroisothiazolinone is often used with methylisothiazolinone (MI). But I was surprised by the number of people who have written in to talk about their experiences. For rinse-off personal care products, we are reducing MI levels globally to ensure we meet new . Methylchloroisothiazolinone is not listed by The International Agency for Research on Cancer (IARC) as a known, probable, or possible human carcinogen. Some examples of cosmetic products that contain MI are: products for children and babies, bath products, makeup (eyeliners, makeup removers, blush and face powder), hair care products (such as dyes and bleaches), nail and waxing products, moisturizing creams, sunscreen and baby wipes. It is a powerful biocide and preservative and is the major active ingredient in the commercial product Kathon(TM). Available online: http://www.safecosmetics.org/get-the-facts/chemicals-of-concern/methylisothiazolinone/January 23, 2017. Here are great invisible. Products with Methylchloroisothiazolinone << Back to the ingredient description Kedma Black Mud Shampoo LR Health & Beauty Propolis Cream Malizia Detergente Intimo Camomilla Nature Republic Argan Essential Deep Care Hair Pack Nature Republic Argan Essential Deep Care Shampoo Nexxus Clean & Pure Conditioner Nexxus Clean & Pure . A number of major brands of personal care products contain methylchloroisothiazolinone (see below), and thus, industry has a stake in how the chemical is perceived, researched, and regulated. We wont share your information and you may opt out at any time. It's most often seen in shampoos and other rinse-off products. [3] [4] Both chemicals inhibit bacterial growth in cosmetic products on their own, but they are most commonly used as a mixture in products. Methylchloroisothiazolinone is a preservative often used in cosmetics and beauty products for its antibacterial and anti-fungal effects, according to Wikipedia. Methylchloroisothiazolinone/methylisothiazolinone and moist wipe dermatitis. All rights reserved. (National Institute of Health,2012) Structure & Function; Methylchloroisothiazolinone has a complexed structure. [16] Cosmetics Europe: the personal care association. Its used to help. Cannot be redeemed for cash, applied to previous purchases or combined with any other promo code. [11] Lundov, M. D., Krongaard, T., Menn, T. L., & Johansen, J. D. (2011). If you have sensitive skin, you should especially avoid products that contain both CMIT and MIT [1]. Products Containing Methylchloroisothiazolinone FILTERS. In personal care products, do your own research on a products ingredients by using a resource such as the Environmental Working Groups Skin Deep product database. Monroe HR, et al. Methylisothiazolinone is found in a multitude of products, including those claiming to be "natural". creams) [10]. Methylchloroisothiazolinone is a heterocyclic compound that functions as a preservative that kills bacteria and fungus which is found in cosmetics and beauty products.It is also found in paints, detergents,glue and fuel storage tanks. creating allergic reactions - often in the form of red itchy rash (contact dermatitis). In Canada, MCI/MI is permitted for rinse-off products and not permitted for leave-in products. Because methylisothiazolinone is a strong cytotoxin, its use is under fire because of its . Methylchloroisothiazolinone. BAD say "It is their presence in personal care products that are causing most concern, for example moist tissue wipes, cleansers, shower gels, deodorants, shaving foam. It is used in concentrations of up to 15% in rinse-off products and 8% in other cosmetics (EWG). If you are not allergic, MIT and CMIT are among the safer preservatives with regard to long-term chronic health effects. [4] US Department of Health & Human Services Household Products Databases. I take a scientific approach to the Curly Girl Method. DOI: The International Agency for Research on Cancer (IARC). Gross. Methylchloroisothiazolinone may be listed as other names on product labels [2] [4] including: CMIT has been linked to allergic reactions, skin, eye & lung irritationand has been restricted for use in the EU, Canada & Japan. . International journal of toxicology, 29(4 suppl), 187S-213S. Cleaning Products; VOC Status: Subscription Only Chemical Formula: Subscription Only Ingredient Type: Subscription Only . Methylchloroisothiazolinone is a potential allergen used in beauty products, although most reactions occurred in the 1980s and 1990s with leave in products, and it is now only used in much lower concentrations and in rinse off products, leading to much lower rates of allergic and irritant reactions, according to research. Although there is some research claiming Methylchloroisothiazolinone causes cancer, no scientific data could be found to prove this link. They are generally used in water-based formulations rather than oil or wax-based products. Final report of the safety assessment of methylisothiazolinone. For babies and young children, be aware that methylchloroisothiazolinone may be baby products that have been labeled hypoallergenic [3] Thats because there are no government standards stipulating criteria for hypoallergenic products. It is also used in glue production, detergents, paints, fuels, and other industrial processes. chemicals of concernproducts of concernlaws and regulationstips, 1388 Sutter Street, Suite 400San Francisco, CA 94109-5400, BCPP is a 501(c)3 | EIN: 94-3155886 | Privacy Policy | Site Map | BCPP.org. Methylchloroisothiazolinone (MCI) is a preservative used in beauty care products, paint, and cleaning products. (n.d.). As of June 2016, children's products with this ingredient can no longer be sold in Canada. Code: WOWCLEAN. Read the ingredients list on the product label and look for any of the following: Methylchloroisothiazolinone (MCI), especially when paired with methylisothiazolinone (MI), is an effective preservative. Methylisothiazolinone, MIT, or MI, is the organic compound with the formula S(CH) 2 C(O)NCH 3.It is a white solid. In high concentrations, MCI can cause chemical burns and its a skin and membrane irritant. It inhibits growth of microorganisms during storage and use. This is an High activity formulation of disinfectants, cleansers and sterilants,fungicidal/algicidal washes,Disinfectant wipes: MOSV BM: Water borne formulation of MIT/BIT EWG VERIFIED PRODUCT TYPE. Healthline Media does not provide medical advice, diagnosis, or treatment. Isododecane: What Are the Benefits and Is It Safe? Methylchloroisothiazolinone and/or methylisothiazolinone in cosmetic products-A market survey Despite the ministerial regulations restricting their use, MCI and/or MI are still found in cosmetics sold on the Thai market. [6] Rohm & Haas (2002). Methylchloroisothiazolinone, also referred to as MCI, is the organic compound with the formula S(C 2 HCl)C(O)N(CH 3). Please try again later! Methylchloroisothiazolinone (MCI) is a preservative that's active against bacteria, yeast, and fungi. Method Products Inc. 637 Commercial St Suite 300 San Francisco, CA 94111 866-963-8463 Emergency Telephone No information available 2. Final report of the safety assessment of methylisothiazolinone. MCI/MI and MI alone were found on the labels of both leave-on and rinse-off products, the presence of each varying between product subcategories. To avoidmethylchloroisothiazolinone, be sure to read ingredient labels and avoid products thatcontaining the ingredients listed above. Helpful how-tos and reviews from Marta and friends. Safety assessment of methylisothiazolinone and methylchlorothiazolinone as used in cosmetics. Preservatives like this are how shampoos can stay in bottles for years without going bad. Isododecane is an ingredient that's used in many different types of beauty and cosmetic products. Learn about butylene glycol, a popular ingredient in cosmetics and skin care products that's generally safe for most people to use. AQUAXYL, a sugar derivative, maintains the . (2019). You can learn more about how we ensure our content is accurate and current by reading our. In the United States, its currently used in concentrations of up to 15 parts per million (ppm) in rinse-off products and 8 ppm in other cosmetics. [5] Found In Shampoo Conditioner Hair color Body wash Burnett CL, et al. Rohm & Haas Chemicals, LLC Report, 06R-1002. Inspiring thoughts and women who are aging gracefully. Because of this, many countries including the United States have restricted the concentration levels of MCI/MI in products. This substance is a preservative used in personal hygiene products (such as shampoos, lotions, emulsions, and sun screens), and in industrial cooling oils, cutting oils, and paper finishes. (2010). Alternative names of isothiazolinone mix. What are the Concerns? Accessed April 26, 2022. What are some products that may contain Methylchloroisothiazinoline / methylisothiazinolone? Filter by. 2005-2022 Healthline Media a Red Ventures Company. A program of Breast Cancer Prevention Partners, Home > Chemicals > Methylisothiazolinone and Methylchloroisothiazolinone, Methylisothiazolinone (MIT) and Methylchloroisothiazolinone (CMIT) are widely used preservatives found in liquid cosmetic and personal care products. It contains: SEPITONIC M3.0, a multimineral cocktail, stimulates cells oxygenation. Methylchloroisothiazolinone/methylisothiazolinone and methylisothiazolinone sensitivity in Hungary. [5] EWGs Guide to Healthier CleaningDatabase. currently registered products in approximately a 3:1 ratio, respectively, and are commonly referred to as methylisothiazolinone. The trouble with methylisothiazolinone and methylchloroisothiazolinone in especially leave-on products (e.g. Clearya alerts you to toxics and helps you find safe products. Methylisothiazolinone is a preservative that's commonly used in personal care products. Methylisothiazolinone (MI) and Methylchloroisothiazolinone (MCI) Also known as Kathon CG, MI is a known skin irritant. Methylchloroisothiazolinone products Find Methylchloroisothiazolinone products, manufacturers, suppliers and exporters. NEWS & INSIGHTS; CONTACT SKIN DEEP; FOR THE MEDIA; EWG is a 501(c)(3) nonprofit . The European Society of Contact Dermatitis has recommended that CMIT no longer be used in leave-on skin products [1]. Since these changes, the rates of allergic and irritant reactions are lower. Outside of shampoos, Methylchloroisothiazolinone and Methylisothiazolinone are also used in paper coatings, paints, glue etc. Rohm & Haas Chemicals, LLC Report, 06R-1002. What Is Blau Syndrome and How Do You Manage It? [14] However, animal studies did not find significant signs of neurotoxicity when rodents were exposed to MIT through drinking water. Methylchloroisothiazolinone (CMIT) is a preservative that is found in a wide array of liquid cosmetics, personal care products and cleaning products on the market today [1]. British Journal of Dermatology, 165(6), 1178-1182. Skin Care: Energizing Essence by Seppic. Methylchloroisothiazolinone/ Methylisothiazolinone is the mixture of the heterocyclic organic compounds Methylchloroisothiazolinone and Methylisothiazolinone that conforms to the formula: C 4 H 4 ClNOS C 4 H 5 NOS. Methylchloroisothiazolinone - Product Ingredients Methylchloroisothiazolinone is the heterocyclic organic compound that conforms to the formula: C<sub>4</sub>H<sub>4</sub>ClNOS. Leave on products may no longer be formulated with this ingredient. It has since been largely removed from the majority of cosmetic products and is now used primarily in rinse-off products in much lower concentrations. Methylchloroisothiazolinone/ Methylisothiazolinone (aka Kathon CG ) Caution Most research that's been done on these two preservatives have been done on how Methylchloroisothiazolinone (and) Methylisothiazolinone work together. It has a role as an antimicrobial agent, a xenobiotic and an environmental contaminant. [5] Burnett, C. L., Bergfeld, W. F., Belsito, D. V., Klaassen, C. D., Marks, J. G., Shank, R. C., & Andersen, F. A. This chemical is used to extend a product's shelf life and protect consumers against exposure to bacteria and mold by inhibiting the growth of those organisms. Accessed April 26, 2022. [1] Campaign for Safe Cosmetics (2016). Methylisothiazolinone (MIT) and Methylchloroisothiazolinone (CMIT) may be hard to pronounce, but they can be even harder on the body. As an ingredient in cosmetics, MCI has been associated with allergic reactions. Its used in the manufacture of water-based cosmetics and personal care products. Methylchloroisothiazolinone 0.03 - 0.13: 96 h Pseudokirchneriella subcapitata mg/L EC50 static 1.6: 96 h Oncorhynchus mykiss mg/L LC50 semi-static
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